Resmed
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EXIT WORM SYRUP

Piperazine Citrate produces a paralysis of muscle in Ascaris resulting in the expulsion of the worm by peristalsis. It has been proposed that piperazine acts on Ascaris muscle by altering the permeability of the cell membrane to ions that are responsible for the maintenance of the resting potential.

The medicine causes hyperpolarization and suppression of spontaneous spike potentials with accompanying paralysis.

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